KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP7
All Species:
27.27
Human Site:
T440
Identified Species:
42.86
UniProt:
Q93009
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93009
NP_003461.2
1102
128302
T440
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Chimpanzee
Pan troglodytes
XP_510806
1102
128297
T440
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536979
1086
126326
T424
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4J8
1103
128457
T441
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Rat
Rattus norvegicus
Q4VSI4
1103
128413
T441
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506396
1145
132881
T483
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Chicken
Gallus gallus
Q6U7I1
1101
128279
T440
L
D
E
F
L
Q
K
T
D
P
K
D
P
A
N
Frog
Xenopus laevis
NP_001121282
534
61718
Zebra Danio
Brachydanio rerio
XP_691215
1103
128646
P441
L
D
E
F
L
Q
K
P
D
V
K
D
P
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYQ8
1129
130428
E466
N
L
D
R
Y
L
A
E
S
E
N
T
L
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKC3
1135
131579
M418
S
C
C
E
L
G
P
M
L
T
E
E
D
C
V
Sea Urchin
Strong. purpuratus
XP_780569
1189
136707
E535
N
L
D
T
F
M
K
E
E
E
E
T
S
A
D
Poplar Tree
Populus trichocarpa
XP_002316470
1116
130731
A429
G
K
Y
L
S
P
E
A
D
C
S
V
R
N
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU2
1115
130630
A430
G
R
Y
L
S
P
D
A
D
K
S
V
R
N
L
Baker's Yeast
Sacchar. cerevisiae
P50101
1230
143545
N441
K
K
T
L
D
S
E
N
K
D
K
N
P
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.7
N.A.
99
99
N.A.
92.4
95.9
46
94
N.A.
48.5
N.A.
34.4
54.5
Protein Similarity:
100
99.9
N.A.
98
N.A.
99.7
99.8
N.A.
94.7
97.9
47.4
96.8
N.A.
67.5
N.A.
52.5
69.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
86.6
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
86.6
N.A.
20
N.A.
20
40
Percent
Protein Identity:
36.9
N.A.
N.A.
36.5
29.4
N.A.
Protein Similarity:
54.3
N.A.
N.A.
54.7
47.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
14
0
0
0
0
0
67
0
% A
% Cys:
0
7
7
0
0
0
0
0
0
7
0
0
0
7
0
% C
% Asp:
0
54
14
0
7
0
7
0
67
7
0
54
7
0
14
% D
% Glu:
0
0
54
7
0
0
14
14
7
14
14
7
0
0
0
% E
% Phe:
0
0
0
54
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
14
0
0
0
0
60
0
7
7
60
0
0
0
0
% K
% Leu:
54
14
0
20
60
7
0
0
7
0
0
0
7
0
14
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
7
0
0
7
7
0
14
54
% N
% Pro:
0
0
0
0
0
14
7
7
0
47
0
0
60
0
0
% P
% Gln:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
0
0
14
0
0
% R
% Ser:
7
0
0
0
14
7
0
0
7
0
14
0
7
0
0
% S
% Thr:
0
0
7
7
0
0
0
47
0
7
0
14
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
14
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
7
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _